My typical "desktop" consists of two environments: the local machine (usually my notebook) and a VNC session to some fancier hardware. The logic behind this is that I can play around with my local apps and even reboot if I need to without losing any real work, which is usually done on the remote machine.
This works out quite well except for sharing information between environments. Quite often I'm browsing a web site inside the VNC session and want to open it up in my local environment, to have access to multimedia features or simply not to bloat my pristine remote session. Trouble is that X11 has a concept called the "cutbuffer" and another for "selections", which depend on which apps you're running. And, you've guessed it, VNC syncronizes the wrong one (namely the cutbuffer). So to simply copy a URL between sessions I had to select the URL using the mouse, paste it (middle-click) into an xterm window, select it again (!), switch to the other environment, paste it (middle-click again) into another xterm, then re-select it, and finally paste it into my other browser. This took care of syncing all of the related buffers manually.
Today I finally got fed up with it after doing this 3 times within 10 minutes. I found a project called autocutsel that does this automatically for me. Now all I have to do is keep autocutsel running in the background, and every time I copy something inside the local browser (using Ctrl-C) it is instantly available for use inside the VNC session (and vice-versa if I run autocutsel both in my local and my remote VNC environments).